6VL4
Crystal Structure of mPGES-1 bound to DG-031
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Prostaglandin E synthase | polymer | 154 | 17323.6 | 1 | UniProt (O14684) Pfam (PF01124) | Homo sapiens (Human) | Microsomal glutathione S-transferase 1-like 1,MGST1-L1,Microsomal prostaglandin E synthase 1,MPGES-1,p53-induced gene 12 protein |
| 2 | B (A) | (2R)-cyclopentyl{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid | non-polymer | 361.4 | 1 | Chemie (QY1) | |||
| 3 | C (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 1 | Chemie (BOG) | |||
| 4 | D, E (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 5 | F (A) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
A: 2 - 152 (UniProt: O14684)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Ala 0 | - | expression tag |
| Leu 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17323.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1042.3 | |
| All* | Total formula weight | 18365.8 |
