6VKM

Crystal Structure of Stabilized GP from Makona Variant of Ebola Virus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Virion spike glycoprotein	polymer	494	55446.4	1	UniProt (A0A2I4PEY8) UniProt (A0A0E3XL33) Pfam (PF01611) Pfam (PF22307) UniProt (by SIFTS) (Q05320)	Zaire ebolavirus
2	B (B)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
3	C (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A: 1 - 472 (UniProt: A0A2I4PEY8)

PDB	External Database	Details
Ala 42	Thr 42	engineered mutation

A: 473 - 647 (UniProt: A0A0E3XL33)

PDB	External Database	Details
Pro 577	Thr 577	engineered mutation
Phe 588	Lys 588	engineered mutation
His 648	-	expression tag
His 649	-	expression tag
His 650	-	expression tag
His 651	-	expression tag
His 652	-	expression tag
His 653	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	55446.4
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	56092.1

*Water molecules are not included.