6VJU

Crystal Structure of Cystathionine beta synthase from Legionella pneumophila with LLP, PLP, and homocysteine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Cystathionine beta-lyase	polymer	324	35656.7	1	UniProt (A0A2S6F0T8) Pfam (PF00291) UniProt (by SIFTS) (Q5ZRD1)	Legionella pneumophila
2	B (B)	Cystathionine beta-lyase	polymer	324	35428.6	1	UniProt (A0A2S6F0T8) Pfam (PF00291) UniProt (by SIFTS) (Q5ZRD1)	Legionella pneumophila
3	C, D, E, H, M... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	10	Chemie (EDO)
4	F, G, I, J, L... (A, B)	ACETATE ION	non-polymer		59.0	7	Chemie (ACT)
5	K (A)	2-AMINO-4-MERCAPTO-BUTYRIC ACID	non-polymer		135.2	1	Chemie (HCS)
6	S (B)	PYRIDOXAL-5'-PHOSPHATE	non-polymer		247.1	1	Chemie (PLP)
7	V, W (A, B)	water	water		18.0	598	Chemie (HOH)

Sequence modifications

A: 9 - 324 (UniProt: A0A2S6F0T8)

PDB	External Database	Details
Met 1	-	initiating methionine
Ala 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag

B: 9 - 324 (UniProt: A0A2S6F0T8)

PDB	External Database	Details
Met 1	-	initiating methionine
Ala 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71085.3
Non-Polymers*	Number of molecules	19
	Total formula weight	1416.3
All*	Total formula weight	72501.6

*Water molecules are not included.