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6VJS

Escherichia coli RNA polymerase and ureidothiophene-2-carboxylic acid complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, F, G
(A, B, F, G)
DNA-directed RNA polymerase subunit alphapolymer32936558.74UniProt (P0A7Z4)
Pfam (PF01193)
Pfam (PF01000)
Pfam (PF03118)
Escherichia coliRNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2C, H
(C, H)
DNA-directed RNA polymerase subunit betapolymer1342150820.92UniProt (P0A8V4)
Pfam (PF04560)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF10385)
Pfam (PF00562)
UniProt (by SIFTS) (P0A8V2)
Escherichia coliRNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3D, I
(D, I)
DNA-directed RNA polymerase subunit beta'polymer1407155366.82UniProt (P0A8T7)
Pfam (PF04997)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Escherichia coliRNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
4E, J
(E, J)
DNA-directed RNA polymerase subunit omegapolymer9110249.52UniProt (P0A802)
Pfam (PF01192)
UniProt (by SIFTS) (P0A800)
Escherichia coliRNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
5K, L
(X, Y)
RNA polymerase sigma factor RpoDpolymer61370352.22UniProt (Q0P6L9)
Pfam (PF03979)
Pfam (PF00140)
Pfam (PF04546)
Pfam (PF04542)
Pfam (PF04539)
Pfam (PF04545)
UniProt (by SIFTS) (P00579)
Escherichia coliSigma-70
6M
(D)
3-{[benzyl(ethyl)carbamoyl]amino}-5-(4-phenoxyphenyl)thiophene-2-carboxylic acidnon-polymer472.61Chemie (QZY)
7N, O, Q, R
(D, I)
ZINC IONnon-polymer65.44Chemie (ZN)
8P, S
(D, I)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight919813.6
Non-Polymers*Number of molecules7
Total formula weight782.8
All*Total formula weight920596.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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