6VJS

Escherichia coli RNA polymerase and ureidothiophene-2-carboxylic acid complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, F, G	DNA-directed RNA polymerase subunit alpha	polymer	329	36558.7	4	UniProt (P0A7Z4) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB	Escherichia coli	RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2	C, H	DNA-directed RNA polymerase subunit beta	polymer	1342	150820.9	2	UniProt (P0A8V4) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) UniProt (by SIFTS) (P0A8V2) In PDB	Escherichia coli	RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3	D, I	DNA-directed RNA polymerase subunit beta'	polymer	1407	155366.8	2	UniProt (P0A8T7) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB	Escherichia coli	RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
4	E, J	DNA-directed RNA polymerase subunit omega	polymer	91	10249.5	2	UniProt (P0A802) Pfam (PF01192) UniProt (by SIFTS) (P0A800) In PDB	Escherichia coli	RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
5	X, Y	RNA polymerase sigma factor RpoD	polymer	613	70352.2	2	UniProt (Q0P6L9) Pfam (PF03979) Pfam (PF00140) Pfam (PF04546) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) UniProt (by SIFTS) (P00579) In PDB	Escherichia coli	Sigma-70
6	D	3-{[benzyl(ethyl)carbamoyl]amino}-5-(4-phenoxyphenyl)thiophene-2-carboxylic acid	non-polymer		472.6	1	Chemie (QZY)
7	D, I	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
8	D, I	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	919813.6
Non-Polymers*	Number of molecules	7
	Total formula weight	782.8
All*	Total formula weight	920596.4

*Water molecules are not included.