6VJE
Crystal structure of Pseudomonas aeruginosa penicillin-binding protein 3 (PBP3) complexed with ceftobiprole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidoglycan D,D-transpeptidase FtsI | polymer | 538 | 58329.5 | 1 | UniProt (Q51504) Pfam (PF03717) Pfam (PF00905) UniProt (by SIFTS) (G3XD46) | Pseudomonas aeruginosa | Penicillin-binding protein 3,PBP-3 |
| 2 | B (A) | (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | non-polymer | 536.6 | 1 | Chemie (RB6) | |||
| 3 | C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | E (A) | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence modifications
A: 50 - 579 (UniProt: Q51504)
| PDB | External Database | Details |
|---|---|---|
| Met 42 | - | initiating methionine |
| Gly 43 | - | expression tag |
| His 44 | - | expression tag |
| His 45 | - | expression tag |
| His 46 | - | expression tag |
| His 47 | - | expression tag |
| His 48 | - | expression tag |
| His 49 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58329.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 607.5 | |
| All* | Total formula weight | 58936.9 |
