6VIY
BRD2_Bromodomain2 complex with pyrrolopyridone compound 27
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bromodomain-containing protein 2 | polymer | 112 | 13184.1 | 2 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
| 2 | A | 4-[2-(2,6-dimethylphenoxy)-5-(ethylsulfonyl)phenyl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide | non-polymer | 507.6 | 1 | Chemie (QYY) | |||
| 3 | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A, B: 348 - 455 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Gly 344 | - | expression tag |
| Ser 345 | - | expression tag |
| His 346 | - | expression tag |
| Met 347 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26368.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 507.6 | |
| All* | Total formula weight | 26875.9 |
