6VIW
BRD4_Bromodomain1 complex with pyrrolopyridone compound 18
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Bromodomain-containing protein 4 | polymer | 116 | 13923.1 | 3 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
| 2 | A, B, C | 4-[2-(2,4-difluorophenoxy)-5-(methylsulfonyl)phenyl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide | non-polymer | 501.5 | 3 | Chemie (QYV) | |||
| 3 | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A, B, C: 57 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Gly 53 | - | expression tag |
| Ser 54 | - | expression tag |
| His 55 | - | expression tag |
| Met 56 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 41769.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1504.5 | |
| All* | Total formula weight | 43273.8 |
