6VE5
X-ray structure of human REV7 in complex with Shieldin3 (residues 41-74)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitotic spindle assembly checkpoint protein MAD2B | polymer | 215 | 24630.7 | 1 | UniProt (Q9UI95) Pfam (PF02301) | Homo sapiens (Human) | Mitotic arrest deficient 2-like protein 2,MAD2-like protein 2,REV7 homolog,hREV7 |
| 2 | B (B) | Shieldin complex subunit 3 | polymer | 35 | 4067.7 | 1 | UniProt (Q6ZNX1) | Homo sapiens (Human) | REV7-interacting novel NHEJ regulator 1,Shield complex subunit 3 |
| 3 | C, D, E (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A: 1 - 211 (UniProt: Q9UI95)
B: 41 - 74 (UniProt: Q6ZNX1)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 124 | Arg 124 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 40 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28698.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 28986.6 |
