6VCD
Cryo-EM structure of IRP2-FBXL5-SKP1 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Iron-responsive element binding protein 2, isoform CRA_a | polymer | 963 | 105165.3 | 1 | UniProt (D3DW85) Pfam (PF00330) Pfam (PF00694) UniProt (by SIFTS) (P48200) In PDB | Homo sapiens (Human) | IRP2 |
| 2 | B | F-box/LRR-repeat protein 5 | polymer | 492 | 54832.4 | 1 | UniProt (Q9UKA1) Pfam (PF12937) Pfam (PF13516) In PDB | Homo sapiens (Human) | FBXL5,F-box and leucine-rich repeat protein 5,F-box protein FBL4/FBL5,p45SKP2-like protein |
| 3 | C | S-phase kinase-associated protein 1 | polymer | 163 | 18680.0 | 1 | UniProt (P63208) Pfam (PF03931) Pfam (PF01466) In PDB | Homo sapiens (Human) | SKP1,Cyclin-A/CDK2-associated protein p19,p19A,Organ of Corti protein 2,OCP-2,Organ of Corti protein II,OCP-II,RNA polymerase II elongation factor-like protein,SIII,Transcription elongation factor B polypeptide 1-like,p19skp1 |
| 4 | B | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 1 | Chemie (FES) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 178677.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 175.8 | |
| All* | Total formula weight | 178853.6 |
