6VAH
Crystal structure of human TEAD2 transcription factor in complex with Flufenamic acid derivative
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transcriptional enhancer factor TEF-4 | polymer | 240 | 27489.1 | 2 | UniProt (Q15562) Pfam (PF17725) | Homo sapiens (Human) | TEA domain family member 2,TEAD-2 |
| 2 | C, D (A, B) | 2-fluoro-6-[(3-hexylphenyl)amino]benzoic acid | non-polymer | 315.4 | 2 | Chemie (QZ1) | |||
| 3 | E (B) | UNKNOWN ATOM OR ION | non-polymer | 1 | Chemie (UNX) | ||||
| 4 | F, G (A, B) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A, B: 217 - 447 (UniProt: Q15562)
| PDB | External Database | Details |
|---|---|---|
| Met 216 | - | initiating methionine |
| Val 448 | - | expression tag |
| Glu 449 | - | expression tag |
| His 450 | - | expression tag |
| His 451 | - | expression tag |
| His 452 | - | expression tag |
| His 453 | - | expression tag |
| His 454 | - | expression tag |
| His 455 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54978.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 630.8 | |
| All* | Total formula weight | 55609.0 |
