6V8F
Crystal structure of recombinat mutant Q185R of human fumarase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fumarate hydratase, mitochondrial | polymer | 466 | 50168.5 | 2 | UniProt (P07954) Pfam (PF00206) Pfam (PF10415) | Homo sapiens (Human) | HsFH |
| 2 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | E, G (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | F, H (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 603 | Chemie (HOH) |
Sequence modifications
A, B: 45 - 510 (UniProt: P07954)
| PDB | External Database | Details |
|---|---|---|
| Arg 185 | Gln 185 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100336.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 447.2 | |
| All* | Total formula weight | 100784.1 |
