6V8D
Design, Synthesis, and Mechanism of Fluorine-substituted Cyclohexene Analogues of GAMA-Aminobutyric Acid (GABA) as Selective Ornithine Aminotransferase Inactivators
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Ornithine aminotransferase, mitochondrial | polymer | 404 | 44860.3 | 3 | UniProt (P04181) Pfam (PF00202) | Homo sapiens (Human) | Ornithine delta-aminotransferase,Ornithine--oxo-acid aminotransferase |
| 2 | D, F, H (A, B, C) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 3 | Chemie (PLP) | |||
| 3 | E, G, I (A, B, C) | (3Z)-3-iminocyclohex-1-ene-1-carboxylic acid | non-polymer | 139.2 | 3 | Chemie (O78) | |||
| 4 | J, K, L (A, B, C) | water | water | 18.0 | 547 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 134581.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1158.9 | |
| All* | Total formula weight | 135739.8 |
