6V6U
Crystal structure of RhoA-GDP with novel Switch I conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transforming protein RhoA | polymer | 183 | 20578.5 | 1 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (Human) | Rho cDNA clone 12,h12 |
| 2 | B (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D, E (A) | 1,4-DIETHYLENE DIOXIDE | non-polymer | 88.1 | 2 | Chemie (DIO) | |||
| 5 | F (A) | water | water | 18.0 | 201 | Chemie (HOH) |
Sequence modifications
A: 1 - 181 (UniProt: P61586)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asn 25 | Phe 25 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20578.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 643.7 | |
| All* | Total formula weight | 21222.2 |
