6V63
SETD3 WT in Complex with an Actin Peptide with His73 Replaced with Glutamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (Y, Z) | Actin, cytoplasmic 1 | polymer | 23 | 2858.2 | 2 | UniProt (C9JUM1) UniProt (by SIFTS) (P63261) | Homo sapiens | |
| 2 | B, D (A, B) | Actin-histidine N-methyltransferase | polymer | 596 | 67486.2 | 2 | UniProt (Q86TU7) Pfam (PF00856) Pfam (PF09273) | Homo sapiens (Human) | SET domain-containing protein 3,hSETD3 |
| 3 | E, G (Y, A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | DA, F (B, A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 5 | AA, BA, CA, EA, FA... (A, Z, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 36 | Chemie (EDO) | |||
| 6 | Z (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | TA, UA, VA, WA (Y, A, Z, B) | water | water | 18.0 | 667 | Chemie (HOH) |
Sequence modifications
Y, Z: 66 - 88 (UniProt: C9JUM1)
A, B: 0 - 593 (UniProt: Q86TU7)
| PDB | External Database | Details |
|---|---|---|
| Gln 73 | His 73 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 140688.8 | |
| Non-Polymers* | Number of molecules | 41 |
| Total formula weight | 3246.5 | |
| All* | Total formula weight | 143935.3 |
