6V5A
Crystal structure of the human BK channel gating ring L390P mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcium-activated potassium channel subunit alpha-1 | polymer | 726 | 81628.4 | 1 | UniProt (Q12791) Pfam (PF22614) Pfam (PF03493) Pfam (PF21014) | Homo sapiens (Human) | BK channel,BKCA alpha,Calcium-activated potassium channel,subfamily M subunit alpha-1,K(VCA)alpha,KCa1.1,Maxi K channel,MaxiK,Slo-alpha,Slo1,Slowpoke homolog,hSlo |
| 2 | B (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence modifications
A: 341 - 1056 (UniProt: Q12791)
| PDB | External Database | Details |
|---|---|---|
| Met 340 | - | initiating methionine |
| Pro 390 | Leu 455 | engineered mutation |
| Ser 1057 | - | expression tag |
| Asn 1058 | - | expression tag |
| Ser 1059 | - | expression tag |
| Leu 1060 | - | expression tag |
| Glu 1061 | - | expression tag |
| Val 1062 | - | expression tag |
| Leu 1063 | - | expression tag |
| Phe 1064 | - | expression tag |
| Gln 1065 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 81628.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 136.1 | |
| All* | Total formula weight | 81764.5 |
