6V4G

Crystal Structure Analysis of Zebra fish MDMX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein Mdm4	polymer	104	12130.0	1	UniProt (Q7ZUW7) Pfam (PF02201) In PDB	Danio rerio (Zebrafish)	Double minute 4 protein,Mdm2-like p53-binding protein,Protein Mdmx,p53-binding protein Mdm4
2	B	Stapled peptide QSQQTF(0EH)NLWRLE(MK8)QN(NH2)	polymer	17	2087.4	1		Homo sapiens
3	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4		water	water		18.0	94	Chemie (HOH)

Sequence modifications

A: 15 - 106 (UniProt: Q7ZUW7)

PDB	External Database	Details
Met 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Asp 10	-	expression tag
Asp 11	-	expression tag
Asp 12	-	expression tag
Asp 13	-	expression tag
Lys 14	-	expression tag
Val 46	Leu 46	engineered mutation
Leu 95	Val 95	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	14217.4
Non-Polymers*	Number of molecules	1
	Total formula weight	96.1
All*	Total formula weight	14313.4

*Water molecules are not included.