6V4E

Crystal Structure Analysis of Zebra Fish MDM

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein Mdm4	polymer	104	12130.0	2	UniProt (Q7ZUW7) Pfam (PF02201)	Danio rerio (Zebrafish)	Double minute 4 protein,Mdm2-like p53-binding protein,Protein Mdmx,p53-binding protein Mdm4
2	C, D (C, D)	Stapled peptide QSQQTF(0EH)NLWRLL(MK8)QN(NH2)	polymer	17	2071.4	2		Homo sapiens
3	E, F, G, H (A, B, C, D)	water	water		18.0	121	Chemie (HOH)

Sequence modifications

A, B: 15 - 106 (UniProt: Q7ZUW7)

PDB	External Database	Details
Met 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Asp 10	-	expression tag
Asp 11	-	expression tag
Asp 12	-	expression tag
Asp 13	-	expression tag
Lys 14	-	expression tag
Val 46	Leu 46	engineered mutation
Leu 95	Val 95	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	28402.8
All*	Total formula weight	28402.8

*Water molecules are not included.