6V38
Cryo-EM structure of Ca2+-bound hsSlo1 channel
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Calcium-activated potassium channel subunit alpha-1 | polymer | 1065 | 119988.1 | 4 | UniProt (Q12791) Pfam (PF00520) Pfam (PF03493) Pfam (PF21014) In PDB | Homo sapiens (Human) | BK channel,BKCA alpha,Calcium-activated potassium channel,subfamily M subunit alpha-1,K(VCA)alpha,KCa1.1,Maxi K channel,MaxiK,Slo-alpha,Slo1,Slowpoke homolog,hSlo |
| 2 | A, C, B, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | A, C, B, D | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 4 | B, D, A, C | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 32 | Chemie (POV) | |||
| 5 | B, D, A, C | CHOLESTEROL | non-polymer | 386.7 | 12 | Chemie (CLR) |
Sequence modifications
A, B, C, D: 1 - 1056 (UniProt: Q12791)
| PDB | External Database | Details |
|---|---|---|
| Ser 1057 | - | expression tag |
| Asn 1058 | - | expression tag |
| Ser 1059 | - | expression tag |
| Leu 1060 | - | expression tag |
| Glu 1061 | - | expression tag |
| Val 1062 | - | expression tag |
| Leu 1063 | - | expression tag |
| Phe 1064 | - | expression tag |
| Gln 1065 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 479952.2 | |
| Non-Polymers* | Number of molecules | 56 |
| Total formula weight | 29380.1 | |
| All* | Total formula weight | 509332.4 |
