6V1O

Structure of OXA-48 bound to QPX7728 at 1.80 A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	OXA family beta-lactamase	polymer	263	30869.9	4	UniProt (A0A482LRD5) Pfam (PF00905) UniProt (by SIFTS) (Q6XEC0) In PDB	Klebsiella pneumoniae
2	A, B, C, D	(1aR,7bS)-5-fluoro-2-hydroxy-1,1a,2,7b-tetrahydrocyclopropa[c][1,2]benzoxaborinine-4-carboxylic acid	non-polymer		222.0	4	Chemie (RM9)
3	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)
4	A, C	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5		water	water		18.0	1463	Chemie (HOH)

Sequence modifications

A, B, C, D: 25 - 265 (UniProt: A0A482LRD5)

PDB	External Database	Details
Met 3	-	expression tag
Lys 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Met 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
Glu 18	-	expression tag
Asn 19	-	expression tag
Leu 20	-	expression tag
Tyr 21	-	expression tag
Phe 22	-	expression tag
Gln 23	-	expression tag
Gly 24	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	123479.5
Non-Polymers*	Number of molecules	14
	Total formula weight	1153.3
All*	Total formula weight	124632.8

*Water molecules are not included.