6V00
structure of human KCNQ1-KCNE3-CaM complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D, G, J | Potassium voltage-gated channel subfamily KQT member 1 | polymer | 557 | 63258.6 | 4 | UniProt (P51787) Pfam (PF00520) Pfam (PF07885) Pfam (PF03520) In PDB | Homo sapiens (Human) | IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1,KQT-like 1,Voltage-gated potassium channel subunit Kv7.1 |
2 | B, E, H, K | Calmodulin-1 | polymer | 149 | 16852.5 | 4 | UniProt (P0DP23) Pfam (PF13499) In PDB | Homo sapiens (Human) | |
3 | C, F, I, L | MCherry fluorescent protein,Potassium voltage-gated channel subfamily E member 3 | polymer | 355 | 40095.2 | 4 | UniProt (X5DSL3) UniProt (Q9Y6H6) Pfam (PF01353) Pfam (PF02060) In PDB | Anaplasma marginale | MinK-related peptide 2,Minimum potassium ion channel-related peptide 2,Potassium channel subunit beta MiRP2 |
4 | B, E, H, K | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) |
Sequence modifications
A, D, G, J: 76 - 620 (UniProt: P51787)
C, F, I, L: -249 - -14 (UniProt: X5DSL3)
C, F, I, L: 1 - 103 (UniProt: Q9Y6H6)
PDB | External Database | Details |
---|---|---|
Met 75 | - | expression tag |
Ser 621 | - | expression tag |
Asn 622 | - | expression tag |
Ser 623 | - | expression tag |
Leu 624 | - | expression tag |
Glu 625 | - | expression tag |
Val 626 | - | expression tag |
Leu 627 | - | expression tag |
Phe 628 | - | expression tag |
Gln 629 | - | expression tag |
Gly 630 | - | expression tag |
Pro 631 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -251 | - | expression tag |
Gly -250 | - | expression tag |
Asn -153 | Lys 97 | conflict |
Cys -107 | Lys 143 | conflict |
Arg -106 | Lys 144 | conflict |
Thr -98 | Ser 152 | conflict |
Asp -49 | Asn 201 | conflict |
Leu -43 | Thr 207 | conflict |
Gly -13 | - | linker |
Ser -12 | - | linker |
Gly -11 | - | linker |
Glu -10 | - | linker |
Asn -9 | - | linker |
Leu -8 | - | linker |
Tyr -7 | - | linker |
Phe -6 | - | linker |
Gln -5 | - | linker |
Ser -4 | - | linker |
Ser -3 | - | linker |
Arg -2 | - | linker |
Ala -1 | - | linker |
Thr 0 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 480825.1 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 320.6 | |
All* | Total formula weight | 481145.8 |