6UYH
Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with halofuginone and AMPPNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Prolyl-tRNA synthetase | polymer | 513 | 59537.6 | 2 | Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) UniProt (by SIFTS) (A0A4V8H034) | Naegleria fowleri (Brain eating amoeba) | |
| 2 | C, U (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 3 | D, V (A, B) | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one | non-polymer | 414.7 | 2 | Chemie (HFG) | |||
| 4 | E, W (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | AA, BA, CA, DA, EA... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 21 | Chemie (EDO) | |||
| 6 | J, X (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | FA, GA (A, B) | water | water | 18.0 | 888 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119075.2 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 3385.9 | |
| All* | Total formula weight | 122461.1 |
