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6UYG

Structure of Hepatitis C Virus Envelope Glycoprotein E2c3 core from genotype 6a bound to broadly neutralizing antibody AR3A and non neutralizing antibody E1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(E)
Envelope glycoprotein E2polymer18920707.41Pfam (PF01560)
UniProt (by SIFTS) (B9V0E2)
Recombinant Hepatitis C virus HK6a/JFH-1
2B
(H)
Fab AR3A heavy chainpolymer23224581.41Homo sapiens (Human)
3C
(L)
Fab AR3A light chainpolymer21423296.81Homo sapiens (Human)
4D
(A)
Fab E1 heavy chainpolymer22723938.01Homo sapiens (Human)
5E
(B)
Fab E1 light chainpolymer21924051.81Homo sapiens (Human)
6F
(G)
Immunoglobulin G-binding protein Gpolymer616657.41UniProt (P19909)
Pfam (PF01378)
Streptococcus sp.IgG-binding protein G
7G
(C)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
8H, I
(E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
Sequence modifications
G: 2 - 61 (UniProt: P19909)
PDBExternal DatabaseDetails
Met 1-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight123232.7
BranchedNumber of molecules1
Total formula weight424.4
Non-Polymers*Number of molecules2
Total formula weight442.4
All*Total formula weight124099.5
*Water molecules are not included.

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PDB entries from 2025-10-29

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