6UWK
Engineered variant of I-OnuI meganuclease with improved stability and fully altered specificity targeting human chromosome 11 trans integration site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | I-OnuI-e-Therm-hChr11v3 | polymer | 296 | 34276.0 | 1 | synthetic construct | ||
| 2 | B (B) | DNA (27-MER) | polymer | 27 | 8204.3 | 1 | synthetic construct | ||
| 3 | C (C) | DNA (27-MER) | polymer | 27 | 8391.4 | 1 | synthetic construct | ||
| 4 | D, E, F, G, H... (A) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 5 | L (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | M, N, O (A, B, C) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50871.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 382.7 | |
| All* | Total formula weight | 51254.3 |
