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6UW4

Cryo-EM structure of human TRPV3 determined in lipid nanodisc

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DTransient receptor potential cation channel subfamily V member 3polymer79090728.84UniProt (Q8NET8)
Pfam (PF12796)
Pfam (PF00023)
Pfam (PF00520)
In PDB
Homo sapiens (Human)TrpV3,Vanilloid receptor-like 3,VRL-3
2A, B, C, D[(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoatenon-polymer718.020Chemie (6OU)
3ASODIUM IONnon-polymer23.01Chemie (NA)
Sequence modifications
A, B, C, D: 1 - 790 (UniProt: Q8NET8)
PDBExternal DatabaseDetails
Val 25Ile 25variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight362915.2
Non-Polymers*Number of molecules21
Total formula weight14382.9
All*Total formula weight377298.1
*Water molecules are not included.

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PDB entries from 2024-07-24

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