6UW0
Engineered variant of I-OnuI meganuclease with improved thermostability and fully altered specificity targeting cholera toxin A subunit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | I-OnuI-e-Therm-bCtxA | polymer | 296 | 34146.8 | 2 | synthetic construct | ||
| 2 | C, E (C, E) | DNA (27-MER) | polymer | 27 | 8344.4 | 2 | synthetic construct | ||
| 3 | D, F (D, F) | DNA (27-MER) | polymer | 27 | 8247.4 | 2 | synthetic construct | ||
| 4 | G, H, K, L, M (A, B, D) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 5 | I, J, N (A, F) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | O, P, Q (A, B, F) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 101477.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 386.6 | |
| All* | Total formula weight | 101863.7 |
