6UUH
Crystal structure of broad and potent HIV-1 neutralizing antibody 438-B11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (C, A) | B11 Fab Heavy Chain | polymer | 235 | 25291.6 | 2 | Homo sapiens (Human) | ||
| 2 | B, E (D, B) | B11 Fab Light Chain | polymer | 215 | 23445.0 | 2 | Homo sapiens (Human) | ||
| 3 | C, F (E, F) | Immunoglobulin G-binding protein G | polymer | 66 | 7348.1 | 2 | UniProt (P19909) Pfam (PF01378) | Streptococcus sp. 'group G' | IgG-binding protein G |
| 4 | G (G) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1422.3 | 1 | In PDB GlyTouCan (G35261RT) | |||
| 5 | H (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
E, F: 2 - 61 (UniProt: P19909)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| His 62 | - | expression tag |
| His 63 | - | expression tag |
| His 64 | - | expression tag |
| His 65 | - | expression tag |
| His 66 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 112169.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1422.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 113812.9 |
