6UQC

Mouse IgG2a Bispecific Fc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (C, D)	Ig gamma-2A chain C region, membrane-bound form	polymer	207	23677.8	2	UniProt (P01865) Pfam (PF07654)	Mus musculus (Mouse)
2	C, D (E, F)	Ig gamma-2A chain C region, membrane-bound form	polymer	207	23786.0	2	UniProt (P01865) Pfam (PF07654)	Mus musculus (Mouse)
3	E, F (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1114.0	2	In PDB GlyTouCan (G61751GZ)
4	G, H (G, H)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1317.2	2	In PDB GlyTouCan (G39213VZ)
5	I, K (C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	J, L, M, N (C, D, F)	alpha-L-fucopyranose	non-polymer		164.2	4	Chemie (FUC)
7	O, P, Q, R (C, D, E, F)	water	water		18.0	827	Chemie (HOH)

Sequence modifications

C, D: 237 - 443 (UniProt: P01865)

PDB	External Database	Details
Lys 356	Glu 238	microheterogeneity
Ser 364	Thr 246	microheterogeneity
Asp 409	Lys 291	microheterogeneity
Thr 411	Arg 293	microheterogeneity

E, F: 237 - 443 (UniProt: P01865)

PDB	External Database	Details
Leu 368	Met 250	microheterogeneity
Lys 370	Thr 252	microheterogeneity
Lys 399	Asp 281	microheterogeneity
Glu 439	Lys 321	microheterogeneity

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94927.6
Branched	Number of molecules	4
	Total formula weight	4862.5
Non-Polymers*	Number of molecules	6
	Total formula weight	1099.0
All*	Total formula weight	100889.1

*Water molecules are not included.