6UPA
Crystal Structure of GTPase Domain of Human Septin 2/Septin 6 Heterocomplex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Septin-6 | polymer | 280 | 32081.6 | 1 | UniProt (Q14141) Pfam (PF00735) | Homo sapiens (Human) | |
| 2 | B (A) | Septin-2 | polymer | 299 | 34273.1 | 1 | UniProt (Q15019) Pfam (PF00735) | Homo sapiens (Human) | Neural precursor cell expressed developmentally down-regulated protein 5,NEDD-5 |
| 3 | C (B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 4 | D (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 6 | F, G (B, A) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
B: 40 - 305 (UniProt: Q14141)
A: 35 - 308 (UniProt: Q15019)
| PDB | External Database | Details |
|---|---|---|
| Met 26 | - | initiating methionine |
| Gly 27 | - | expression tag |
| Ser 28 | - | expression tag |
| Ser 29 | - | expression tag |
| His 30 | - | expression tag |
| His 31 | - | expression tag |
| His 32 | - | expression tag |
| His 33 | - | expression tag |
| His 34 | - | expression tag |
| His 35 | - | expression tag |
| Ser 36 | - | expression tag |
| Gln 37 | - | expression tag |
| Asp 38 | - | expression tag |
| Pro 39 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 34 | - | initiating methionine |
| Leu 309 | - | expression tag |
| Glu 310 | - | expression tag |
| Ser 311 | - | expression tag |
| Gly 312 | - | expression tag |
| Lys 313 | - | expression tag |
| Glu 314 | - | expression tag |
| Thr 315 | - | expression tag |
| Ala 316 | - | expression tag |
| Ala 317 | - | expression tag |
| Ala 318 | - | expression tag |
| Lys 319 | - | expression tag |
| Phe 320 | - | expression tag |
| Glu 321 | - | expression tag |
| Arg 322 | - | expression tag |
| Asn 323 | - | expression tag |
| His 324 | - | expression tag |
| Met 325 | - | expression tag |
| Asp 326 | - | expression tag |
| Ser 327 | - | expression tag |
| Ser 328 | - | expression tag |
| Thr 329 | - | expression tag |
| Ser 330 | - | expression tag |
| Ala 331 | - | expression tag |
| Ala 332 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66354.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 990.7 | |
| All* | Total formula weight | 67345.3 |
