6UOZ

Discovery of fragment-inspired heterocyclic benzenesulfonmides as inhibitors of the WDR5-MYC interaction

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	WD repeat domain 5	polymer	304	33492.0	2	UniProt (P61964) Pfam (PF25175)	Homo sapiens
2	C, D (A, B)	5-bromo-3-chloro-N-[1-cyclopentyl-2-(methylsulfonyl)-1H-imidazol-4-yl]-2-hydroxybenzene-1-sulfonamide	non-polymer		498.8	2	Chemie (QF1)
3	E, F (A, B)	water	water		18.0	604	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66984.0
Non-Polymers*	Number of molecules	2
	Total formula weight	997.6
All*	Total formula weight	67981.6

*Water molecules are not included.