6UL0
STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain | polymer | 300 | 34456.5 | 1 | UniProt (Q12306) UniProt (A0A2R3XZB7) Pfam (PF00240) Pfam (PF15009) UniProt (by SIFTS) (Q86WV6) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
2 | A | 4-{5-[(1Z)-3-{[2-(3-carboxypropanoyl)-6-methoxy-1-benzothiophen-5-yl]oxy}prop-1-en-1-yl]-6-methoxy-1-benzothiophen-2-yl}-4-oxobutanoic acid | non-polymer | 582.6 | 1 | Chemie (QBJ) | |||
3 | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A: 51 - 147 (UniProt: Q12306)
A: 155 - 341 (UniProt: A0A2R3XZB7)
PDB | External Database | Details |
---|---|---|
Met 42 | - | initiating methionine |
Ala 43 | - | expression tag |
His 44 | - | expression tag |
His 45 | - | expression tag |
His 46 | - | expression tag |
His 47 | - | expression tag |
His 48 | - | expression tag |
His 49 | - | expression tag |
Gly 50 | - | expression tag |
Thr 113 | Arg 64 | conflict |
Glu 120 | Arg 71 | conflict |
Glu 148 | - | linker |
Asn 149 | - | linker |
Leu 150 | - | linker |
Tyr 151 | - | linker |
Phe 152 | - | linker |
Gln 153 | - | linker |
Ser 154 | - | linker |
PDB | External Database | Details |
---|---|---|
Ala 230 | Gly 230 | engineered mutation |
Gln 293 | Arg 293 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34456.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 582.6 | |
All* | Total formula weight | 35039.2 |