6UKJ
Single-Particle Cryo-EM Structure of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) 7G8 Isoform
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Chloroquine resistance transporter | polymer | 464 | 53074.5 | 1 | UniProt (W7FI62) | Plasmodium falciparum (isolate 7G8) | |
| 2 | B (H) | Fab Heavy Chain | polymer | 241 | 25737.6 | 1 | Homo sapiens (Human) | ||
| 3 | C (L) | Fab Light Chain | polymer | 215 | 23355.9 | 1 | Homo sapiens (Human) | ||
| 4 | D (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (45489984) PubChem (363416) PubChem (60078761) PubChem (500055) PubChem (73440805) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (99567469) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (13301926) PubChem (13301927) PubChem (124914595) PubChem (124914596) PubChem (155804219) PubChem (169132514) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
A: 2 - 424 (UniProt: W7FI62)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | initiating methionine |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Ala 425 | - | expression tag |
| Ala 426 | - | expression tag |
| Ala 427 | - | expression tag |
| Gly 428 | - | expression tag |
| Gly 429 | - | expression tag |
| Gly 430 | - | expression tag |
| Ser 431 | - | expression tag |
| Gly 432 | - | expression tag |
| Gly 433 | - | expression tag |
| Gly 434 | - | expression tag |
| Ser 435 | - | expression tag |
| Glu 436 | - | expression tag |
| Asn 437 | - | expression tag |
| Leu 438 | - | expression tag |
| Tyr 439 | - | expression tag |
| Phe 440 | - | expression tag |
| Gln 441 | - | expression tag |
| Gly 442 | - | expression tag |
| Ser 443 | - | expression tag |
| His 444 | - | expression tag |
| His 445 | - | expression tag |
| His 446 | - | expression tag |
| His 447 | - | expression tag |
| His 448 | - | expression tag |
| His 449 | - | expression tag |
| His 450 | - | expression tag |
| His 451 | - | expression tag |
| His 452 | - | expression tag |
| His 453 | - | expression tag |
| Trp 454 | - | expression tag |
| Ser 455 | - | expression tag |
| His 456 | - | expression tag |
| Pro 457 | - | expression tag |
| Gln 458 | - | expression tag |
| Phe 459 | - | expression tag |
| Glu 460 | - | expression tag |
| Lys 461 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 102168.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 486.7 | |
| All* | Total formula weight | 102654.7 |
