6UJ8
Crystal structure of HLA-B*07:02 with wild-type IDH2 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | HLA class I histocompatibility antigen, B-7 alpha chain | polymer | 298 | 34609.0 | 2 | UniProt (P01889) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | MHC class I antigen B*7 |
| 2 | B, E (B, E) | Beta-2-microglobulin | polymer | 119 | 13732.5 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C, F (C, F) | Isocitrate dehydrogenase [NADP], mitochondrial | polymer | 10 | 1085.2 | 2 | UniProt (P48735) | Homo sapiens | IDH,ICD-M,IDP,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase |
| 4 | G, I, L, N, P... (A, B, D, E) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 6 | Chemie (PEG) | |||
| 5 | H (A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 6 | J, K, Q (A, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | M (B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 8 | O (D) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 9 | S, T, U, V, W... (A, B, C, D, E...) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 280 (UniProt: P01889)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Gly 281 | - | expression tag |
| Ser 282 | - | expression tag |
| Leu 283 | - | expression tag |
| His 284 | - | expression tag |
| His 285 | - | expression tag |
| Ile 286 | - | expression tag |
| Leu 287 | - | expression tag |
| Asp 288 | - | expression tag |
| Ala 289 | - | expression tag |
| Gln 290 | - | expression tag |
| Lys 291 | - | expression tag |
| Met 292 | - | expression tag |
| Val 293 | - | expression tag |
| Trp 294 | - | expression tag |
| Asn 295 | - | expression tag |
| His 296 | - | expression tag |
| Arg 297 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 98853.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1507.6 | |
| All* | Total formula weight | 100361.2 |
