6UJ8

Crystal structure of HLA-B*07:02 with wild-type IDH2 peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0006955	biological_process	immune response
B	0042612	cellular_component	MHC class I protein complex
E	0006955	biological_process	immune response
E	0042612	cellular_component	MHC class I protein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue PEG A 301

Chain	Residue
A	ASP29
A	ASP30
A	1PE302
B	TYR83

---

site_id	AC2
Number of Residues	7
Details	binding site for residue 1PE A 302

Chain	Residue
B	SER72
B	TYR83
A	TYR27
A	ARG48
A	PRO235
A	PHE241
A	PEG301

---

site_id	AC3
Number of Residues	6
Details	binding site for residue PEG A 303

Chain	Residue
A	GLU163
A	GLU166
A	TRP167
A	HOH419
A	HOH450
D	GLU154

---

site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 A 304

Chain	Residue
A	GLU232
A	THR233
A	LYS243

---

site_id	AC5
Number of Residues	2
Details	binding site for residue PEG B 201

Chain	Residue
B	SER77
B	LYS78

---

site_id	AC6
Number of Residues	6
Details	binding site for residue PGE B 202

Chain	Residue
A	PHE8
A	MET98
A	GLN115
B	PHE76
B	SER77
B	LYS78

---

site_id	AC7
Number of Residues	2
Details	binding site for residue PEG B 203

Chain	Residue
B	ILE27
B	LYS111

---

site_id	AC8
Number of Residues	7
Details	binding site for residue PG4 D 301

Chain	Residue
D	TYR27
D	ASP29
D	ASP30
D	THR233
D	PHE241
D	PEG302
E	HOH318

---

site_id	AC9
Number of Residues	3
Details	binding site for residue PEG D 302

Chain	Residue
D	PG4301
D	SO4303
D	HOH447

---

site_id	AD1
Number of Residues	2
Details	binding site for residue SO4 D 303

Chain	Residue
D	PEG302
D	HOH414

---

site_id	AD2
Number of Residues	2
Details	binding site for residue PEG E 201

Chain	Residue
E	PRO25
E	LYS111

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH

Chain	Residue	Details
B	TYR98-HIS104
A	TYR257-HIS263

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	348
Details	Domain: {"description":"Ig-like C1-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	182
Details	Region: {"description":"Alpha-2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	182
Details	Region: {"description":"Alpha-3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Motif: {"description":"Bw6 motif","evidences":[{"source":"PubMed","id":"25480565","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25808313","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"Pyrrolidone carboxylic acid; in form pI 5.3","evidences":[{"source":"PubMed","id":"7554280","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis","evidences":[{"source":"PubMed","id":"7918443","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	12
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) lysine; in vitro","evidences":[{"source":"PubMed","id":"7918443","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P33198","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---