6UIP
DYRK1A Kinase Domain in Complex with a 6-azaindole Derivative, GNF2133.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | polymer | 361 | 42081.5 | 3 | UniProt (Q13627) Pfam (PF00069) In PDB | Homo sapiens (Human) | Dual specificity YAK1-related kinase,HP86,Protein kinase minibrain homolog,hMNB |
2 | A, B, C | 4-ethyl-N-{4-[1-(oxan-4-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]pyridin-2-yl}piperazine-1-carboxamide | non-polymer | 434.5 | 3 | Chemie (Q8J) |
Sequence modifications
A, B, C: 127 - 485 (UniProt: Q13627)
PDB | External Database | Details |
---|---|---|
Ser 125 | - | expression tag |
Met 126 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 126244.6 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1303.6 | |
All* | Total formula weight | 127548.2 |