6UIL
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 7-[(3-aminopropyl)amino]-1,1,1-trifluoroheptan-2-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polyamine deacetylase HDAC10 | polymer | 676 | 75041.6 | 1 | UniProt (F1QCV2) Pfam (PF00850) | Danio rerio | |
| 2 | B (A) | 7-[(3-aminopropyl)amino]-1,1,1-trifluoroheptane-2,2-diol | non-polymer | 258.3 | 1 | Chemie (FKS) | |||
| 3 | C, D (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | F, G (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 6 | H (A) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A: 2 - 675 (UniProt: F1QCV2)
| PDB | External Database | Details |
|---|---|---|
| Ala 1 | - | expression tag |
| Phe 154 | Ile 154 | conflict |
| Thr 548 | Ser 548 | conflict |
| Glu 586 | Gly 586 | conflict |
| Arg 593 | Gly 593 | conflict |
| Arg 596 | Thr 596 | conflict |
| Met 613 | Thr 613 | conflict |
| Pro 646 | Leu 646 | conflict |
| Trp 676 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 75041.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 591.8 | |
| All* | Total formula weight | 75633.4 |
