6UGV
Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a I-centered orthorhombic crystal form, Lot C
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H, A | Infliximab Fab Heavy Chain | polymer | 226 | 24356.2 | 2 | UniProt (A8K008) Pfam (PF07686) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
2 | L, B | Infliximab Fab Light Chain | polymer | 214 | 23460.9 | 2 | UniProt (Q6P5S8) Pfam (PF07686) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
3 | H, A | MESO-ERYTHRITOL | non-polymer | 122.1 | 2 | Chemie (MRY) | |||
4 | H, A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
5 | water | water | 18.0 | 615 | Chemie (HOH) |
Sequence modifications
H, A: 1 - 116 (PDB: 6UGV)
H, A: 117 - 226 (UniProt: A8K008)
L, B: 1 - 106 (PDB: 6UGV)
L, B: 107 - 214 (UniProt: Q6P5S8)
H, A: 117 - 226 (UniProt: A8K008)
L, B: 1 - 106 (PDB: 6UGV)
L, B: 107 - 214 (UniProt: Q6P5S8)
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 95634.1 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 430.4 | |
All* | Total formula weight | 96064.5 |