6UGT

Crystal structure of the Fab fragment of PF06438179/GP1111 an infliximab biosimilar in a I-centered orthorhombic crystal form, Lot A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H, A	PF06438179 Fab Heavy Chain	polymer	226	24356.2	2	UniProt (A8K008) Pfam (PF07686) Pfam (PF07654) In PDB	Homo sapiens (Human)
2	L, B	PF06438179 Fab Light Chain	polymer	214	23460.9	2	UniProt (Q6P5S8) Pfam (PF07686) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	H, L, A, B	1,2-ETHANEDIOL	non-polymer		62.1	7	Chemie (EDO)
4		water	water		18.0	652	Chemie (HOH)

Sequence modifications

H, A: 1 - 116 (PDB: 6UGT)
H, A: 117 - 226 (UniProt: A8K008)
L, B: 1 - 106 (PDB: 6UGT)
L, B: 107 - 214 (UniProt: Q6P5S8)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	95634.1
Non-Polymers*	Number of molecules	7
	Total formula weight	434.5
All*	Total formula weight	96068.6

*Water molecules are not included.