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6UGM

Structural basis of COMPASS eCM recognition of an unmodified nucleosome

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)
Histone H3polymer13515275.92UniProt (Q92133)
Pfam (PF00125)
Xenopus laevis (African clawed frog)
2B, F
(B, F)
Histone H4polymer10211263.22UniProt (P62799)
Pfam (PF15511)
Xenopus laevis (African clawed frog)
3C, G
(C, G)
Histone H2Apolymer10711694.62UniProt (Q6AZJ8)
Pfam (PF00125)
Pfam (PF16211)
Xenopus laevis (African clawed frog)
4D
(D)
Histone H2Bpolymer12513848.11UniProt (A0A1L8FQ56)
Pfam (PF00125)
UniProt (by SIFTS) (P02281)
Xenopus laevis (African clawed frog)
5H
(H)
Histone H2B 1.1polymer12513834.11UniProt (P02281)
Pfam (PF00125)
Xenopus laevis (African clawed frog)H2B1.1
6I
(I)
DNA (146-MER)polymer14745114.71synthetic construct
7J
(J)
DNA (146-MER)polymer14645305.91synthetic construct
8K
(K)
Swd3polymer32736458.91UniProt (Q6CLY5)
Pfam (PF00400)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
9L
(M)
Histone-lysine N-methyltransferase, H3 lysine-4 specificpolymer27531448.51UniProt (Q6CIT4)
Pfam (PF11764)
Pfam (PF00856)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)COMPASS component SET1,SET domain-containing protein 1
10M
(N)
Swd1polymer43949894.71UniProt (Q6CXF3)
Pfam (PF00400)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
11N
(R)
H3 N-terminuspolymer3378.41Xenopus laevis (African clawed frog)
12O
(X)
Spp1polymer34239297.91UniProt (Q6CRQ4)
Pfam (PF00628)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
13P
(L)
Bre2polymer40547287.01UniProt (Q6CTQ1)Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
14Q, R
(O, P)
Sdc1polymer13414722.62UniProt (Q6CPN6)
Pfam (PF05186)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
15S
(M)
S-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
16T
(M)
ZINC IONnon-polymer65.41Chemie (ZN)
Sequence modifications
D: -2 - 122 (UniProt: A0A1L8FQ56)
PDBExternal DatabaseDetails
Pro 7Ala 11conflict
M: 726 - 1000 (UniProt: Q6CIT4)
PDBExternal DatabaseDetails
Glu 761Asp 761conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains18
Total formula weight428780.9
Non-Polymers*Number of molecules2
Total formula weight463.8
All*Total formula weight429244.7
*Water molecules are not included.

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PDB entries from 2025-07-30

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