6UGM
Structural basis of COMPASS eCM recognition of an unmodified nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3 | polymer | 135 | 15275.9 | 2 | UniProt (Q92133) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 2 | B, F (B, F) | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 3 | C, G (C, G) | Histone H2A | polymer | 107 | 11694.6 | 2 | UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) | Xenopus laevis (African clawed frog) | |
| 4 | D (D) | Histone H2B | polymer | 125 | 13848.1 | 1 | UniProt (A0A1L8FQ56) Pfam (PF00125) UniProt (by SIFTS) (P02281) | Xenopus laevis (African clawed frog) | |
| 5 | H (H) | Histone H2B 1.1 | polymer | 125 | 13834.1 | 1 | UniProt (P02281) Pfam (PF00125) | Xenopus laevis (African clawed frog) | H2B1.1 |
| 6 | I (I) | DNA (146-MER) | polymer | 147 | 45114.7 | 1 | synthetic construct | ||
| 7 | J (J) | DNA (146-MER) | polymer | 146 | 45305.9 | 1 | synthetic construct | ||
| 8 | K (K) | Swd3 | polymer | 327 | 36458.9 | 1 | UniProt (Q6CLY5) Pfam (PF00400) | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) | |
| 9 | L (M) | Histone-lysine N-methyltransferase, H3 lysine-4 specific | polymer | 275 | 31448.5 | 1 | UniProt (Q6CIT4) Pfam (PF11764) Pfam (PF00856) | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) | COMPASS component SET1,SET domain-containing protein 1 |
| 10 | M (N) | Swd1 | polymer | 439 | 49894.7 | 1 | UniProt (Q6CXF3) Pfam (PF00400) | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) | |
| 11 | N (R) | H3 N-terminus | polymer | 3 | 378.4 | 1 | Xenopus laevis (African clawed frog) | ||
| 12 | O (X) | Spp1 | polymer | 342 | 39297.9 | 1 | UniProt (Q6CRQ4) Pfam (PF00628) | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) | |
| 13 | P (L) | Bre2 | polymer | 405 | 47287.0 | 1 | UniProt (Q6CTQ1) | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) | |
| 14 | Q, R (O, P) | Sdc1 | polymer | 134 | 14722.6 | 2 | UniProt (Q6CPN6) Pfam (PF05186) | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) | |
| 15 | S (M) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (9865603) PubChem (12312798) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (145712080) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 16 | T (M) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
D: -2 - 122 (UniProt: A0A1L8FQ56)
M: 726 - 1000 (UniProt: Q6CIT4)
| PDB | External Database | Details |
|---|---|---|
| Pro 7 | Ala 11 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Glu 761 | Asp 761 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 428780.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 463.8 | |
| All* | Total formula weight | 429244.7 |
