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6UE6

PWWP1 domain of NSD2 in complex with MR837

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Histone-lysine N-methyltransferase NSD2polymer14116066.58UniProt (O96028)
Pfam (PF00855)
In PDB
Homo sapiens (Human)Multiple myeloma SET domain-containing protein, MMSET, Nuclear SET domain-containing protein 2, Protein trithorax-5, Wolf-Hirschhorn syndrome candidate 1 protein
2C, A, D, H, E...4-cyano-N-cyclopropyl-N-[(thiophen-2-yl)methyl]benzamidenon-polymer282.48Chemie (Q5D)
3B, G, C, A, D...UNKNOWN ATOM OR IONnon-polymer51Chemie (UNX)
Sequence modifications
A, B, C, D, E, F, G, H: 211 - 350 (UniProt: O96028)
PDBExternal DatabaseDetails
Gly 210-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight128531.9
Non-Polymers*Number of molecules59
Total formula weight2258.9
All*Total formula weight130790.8
*Water molecules are not included.

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PDB entries from 2024-07-17

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