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6UDX

X-ray co-crystal structure of compound 7 with Mcl-1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Induced myeloid leukemia cell differentiation protein Mcl-1polymer15717922.32UniProt (Q07820)
Pfam (PF00452)
Homo sapiens (Human)Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT
2C, D
(A, B)
(2R)-[(3S)-6'-chloro-5-(cyclobutylmethyl)-3',4,4',5-tetrahydro-2H,2'H-spiro[1,5-benzoxazepine-3,1'-naphthalen]-7-yl](hydroxy)acetic acidnon-polymer441.92Chemie (Q57)
3E, F
(A, B)
waterwater18.0387Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight35844.7
Non-Polymers*Number of molecules2
Total formula weight883.9
All*Total formula weight36728.6
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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