6UDQ
Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Fully compressed filament end reconstruction.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (I, A, E, J, B...) | Inosine-5'-monophosphate dehydrogenase 2 | polymer | 519 | 56480.5 | 12 | UniProt (P12268) Pfam (PF00478) Pfam (PF00571) | Homo sapiens (Human) | IMPDH 2,IMPDH-II |
| 2 | CA, HA, KA, M, OA... (C, G, D, A, H...) | INOSINIC ACID | non-polymer | 348.2 | 8 | Chemie (IMP) | |||
| 3 | AA, DA, EA, IA, JA... (F, C, G, D, A...) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 16 | Chemie (GTP) | |||
| 4 | BA, FA, GA, NA, P... (F, C, D, A, H...) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 8 | Chemie (ATP) |
Sequence modifications
I, A, E, J, B, F, K, C, G, L, D, H: 1 - 514 (UniProt: P12268)
| PDB | External Database | Details |
|---|---|---|
| Ser -4 | - | expression tag |
| Glu -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 677766.0 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 15214.0 | |
| All* | Total formula weight | 692980.0 |
