6UDQ

Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Fully compressed filament end reconstruction.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	I, A, E, J, B...	Inosine-5'-monophosphate dehydrogenase 2	polymer	519	56480.5	12	UniProt (P12268) Pfam (PF00478) Pfam (PF00571) In PDB	Homo sapiens (Human)	IMPDH 2,IMPDH-II
2	C, G, D, A, H...	INOSINIC ACID	non-polymer		348.2	8	Chemie (IMP)
3	F, C, G, D, A...	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	16	Chemie (GTP)
4	F, C, D, A, H...	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	8	Chemie (ATP)

Sequence modifications

I, A, E, J, B, F, K, C, G, L, D, H: 1 - 514 (UniProt: P12268)

PDB	External Database	Details
Ser -4	-	expression tag
Glu -3	-	expression tag
Phe -2	-	expression tag
Glu -1	-	expression tag
Leu 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	677766.0
Non-Polymers*	Number of molecules	32
	Total formula weight	15214.0
All*	Total formula weight	692980.0

*Water molecules are not included.