6UCV

Cryo-EM structure of the mitochondrial TOM complex from yeast (tetramer)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, I, a, i	Mitochondrial import receptor subunit TOM40	polymer	397	43227.4	4	UniProt (P23644) Pfam (PF01459) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Mitochondrial import site protein ISP42,Translocase of outer membrane 40 kDa subunit
2	B, J, b, j	Mitochondrial import receptor subunit TOM22	polymer	162	18020.7	4	UniProt (P49334) Pfam (PF04281) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Mitochondrial 17 kDa assembly protein,Mitochondrial 22 kDa outer membrane protein,Protein MAS17,Translocase of outer membrane 22 kDa subunit
3	C, K, c, k	Mitochondrial import receptor subunit TOM5	polymer	50	5993.9	4	UniProt (P80967) Pfam (PF10642) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Translocase of outer membrane 5 kDa subunit
4	D, L, d, l	Mitochondrial import receptor subunit TOM6	polymer	61	6410.5	4	UniProt (P33448) Pfam (PF17112) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Mitochondrial import site protein ISP6,Translocase of outer membrane 6 kDa subunit
5	E, M, e, m	Mitochondrial import receptor subunit TOM7	polymer	60	6877.0	4	UniProt (P53507) Pfam (PF08038) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Translocase of outer membrane 7 kDa subunit
6	I, i	1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		677.9	2	Chemie (MC3)

Sequence modifications

A, I, a, i: 1 - 387 (UniProt: P23644)

PDB	External Database	Details
Gly 388	-	expression tag
Gly 389	-	expression tag
Trp 390	-	expression tag
Ser 391	-	expression tag
His 392	-	expression tag
Pro 393	-	expression tag
Gln 394	-	expression tag
Phe 395	-	expression tag
Glu 396	-	expression tag
Lys 397	-	expression tag

B, J, b, j: 1 - 152 (UniProt: P49334)

PDB	External Database	Details
Gly 153	-	expression tag
Gly 154	-	expression tag
His 155	-	expression tag
His 156	-	expression tag
His 157	-	expression tag
His 158	-	expression tag
His 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	20
	Total formula weight	322117.5
Non-Polymers*	Number of molecules	2
	Total formula weight	1355.9
All*	Total formula weight	323473.4

*Water molecules are not included.