6UCV
Cryo-EM structure of the mitochondrial TOM complex from yeast (tetramer)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, K, P (A, I, a, i) | Mitochondrial import receptor subunit TOM40 | polymer | 397 | 43227.4 | 4 | UniProt (P23644) Pfam (PF01459) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Mitochondrial import site protein ISP42,Translocase of outer membrane 40 kDa subunit |
| 2 | B, G, L, Q (B, J, b, j) | Mitochondrial import receptor subunit TOM22 | polymer | 162 | 18020.7 | 4 | UniProt (P49334) Pfam (PF04281) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Mitochondrial 17 kDa assembly protein,Mitochondrial 22 kDa outer membrane protein,Protein MAS17,Translocase of outer membrane 22 kDa subunit |
| 3 | C, H, M, R (C, K, c, k) | Mitochondrial import receptor subunit TOM5 | polymer | 50 | 5993.9 | 4 | UniProt (P80967) Pfam (PF10642) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Translocase of outer membrane 5 kDa subunit |
| 4 | D, I, N, S (D, L, d, l) | Mitochondrial import receptor subunit TOM6 | polymer | 61 | 6410.5 | 4 | UniProt (P33448) Pfam (PF17112) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Mitochondrial import site protein ISP6,Translocase of outer membrane 6 kDa subunit |
| 5 | E, J, O, T (E, M, e, m) | Mitochondrial import receptor subunit TOM7 | polymer | 60 | 6877.0 | 4 | UniProt (P53507) Pfam (PF08038) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Translocase of outer membrane 7 kDa subunit |
| 6 | U, V (I, i) | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 677.9 | 2 | Chemie (MC3) |
Sequence modifications
A, I, a, i: 1 - 387 (UniProt: P23644)
B, J, b, j: 1 - 152 (UniProt: P49334)
| PDB | External Database | Details |
|---|---|---|
| Gly 388 | - | expression tag |
| Gly 389 | - | expression tag |
| Trp 390 | - | expression tag |
| Ser 391 | - | expression tag |
| His 392 | - | expression tag |
| Pro 393 | - | expression tag |
| Gln 394 | - | expression tag |
| Phe 395 | - | expression tag |
| Glu 396 | - | expression tag |
| Lys 397 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 153 | - | expression tag |
| Gly 154 | - | expression tag |
| His 155 | - | expression tag |
| His 156 | - | expression tag |
| His 157 | - | expression tag |
| His 158 | - | expression tag |
| His 159 | - | expression tag |
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| His 162 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 322117.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1355.9 | |
| All* | Total formula weight | 323473.4 |
