Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6UCV

Cryo-EM structure of the mitochondrial TOM complex from yeast (tetramer)

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0005515	molecular_function	protein binding
a	0005739	cellular_component	mitochondrion
a	0005741	cellular_component	mitochondrial outer membrane
a	0005742	cellular_component	mitochondrial outer membrane translocase complex
a	0005758	cellular_component	mitochondrial intermembrane space
a	0005829	cellular_component	cytosol
a	0006811	biological_process	monoatomic ion transport
a	0008320	molecular_function	protein transmembrane transporter activity
a	0015031	biological_process	protein transport
a	0015288	molecular_function	porin activity
a	0030150	biological_process	protein import into mitochondrial matrix
a	0045040	biological_process	protein insertion into mitochondrial outer membrane
a	0046930	cellular_component	pore complex
a	0055085	biological_process	transmembrane transport
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005741	cellular_component	mitochondrial outer membrane
A	0005742	cellular_component	mitochondrial outer membrane translocase complex
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005829	cellular_component	cytosol
A	0006811	biological_process	monoatomic ion transport
A	0008320	molecular_function	protein transmembrane transporter activity
A	0015031	biological_process	protein transport
A	0015288	molecular_function	porin activity
A	0030150	biological_process	protein import into mitochondrial matrix
A	0045040	biological_process	protein insertion into mitochondrial outer membrane
A	0046930	cellular_component	pore complex
A	0055085	biological_process	transmembrane transport
b	0005515	molecular_function	protein binding
b	0005739	cellular_component	mitochondrion
b	0005741	cellular_component	mitochondrial outer membrane
b	0005742	cellular_component	mitochondrial outer membrane translocase complex
b	0006886	biological_process	intracellular protein transport
b	0008320	molecular_function	protein transmembrane transporter activity
b	0015031	biological_process	protein transport
b	0030150	biological_process	protein import into mitochondrial matrix
b	0045040	biological_process	protein insertion into mitochondrial outer membrane
B	0005515	molecular_function	protein binding
B	0005739	cellular_component	mitochondrion
B	0005741	cellular_component	mitochondrial outer membrane
B	0005742	cellular_component	mitochondrial outer membrane translocase complex
B	0006886	biological_process	intracellular protein transport
B	0008320	molecular_function	protein transmembrane transporter activity
B	0015031	biological_process	protein transport
B	0030150	biological_process	protein import into mitochondrial matrix
B	0045040	biological_process	protein insertion into mitochondrial outer membrane
c	0005515	molecular_function	protein binding
c	0005739	cellular_component	mitochondrion
c	0005741	cellular_component	mitochondrial outer membrane
c	0005742	cellular_component	mitochondrial outer membrane translocase complex
c	0006626	biological_process	protein targeting to mitochondrion
c	0008320	molecular_function	protein transmembrane transporter activity
c	0015031	biological_process	protein transport
c	0045040	biological_process	protein insertion into mitochondrial outer membrane
c	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
c	0071806	biological_process	protein transmembrane transport
C	0005515	molecular_function	protein binding
C	0005739	cellular_component	mitochondrion
C	0005741	cellular_component	mitochondrial outer membrane
C	0005742	cellular_component	mitochondrial outer membrane translocase complex
C	0006626	biological_process	protein targeting to mitochondrion
C	0008320	molecular_function	protein transmembrane transporter activity
C	0015031	biological_process	protein transport
C	0045040	biological_process	protein insertion into mitochondrial outer membrane
C	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
C	0071806	biological_process	protein transmembrane transport
d	0005739	cellular_component	mitochondrion
d	0005741	cellular_component	mitochondrial outer membrane
d	0005742	cellular_component	mitochondrial outer membrane translocase complex
d	0008320	molecular_function	protein transmembrane transporter activity
d	0015031	biological_process	protein transport
d	0030150	biological_process	protein import into mitochondrial matrix
d	0045040	biological_process	protein insertion into mitochondrial outer membrane
d	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
D	0005739	cellular_component	mitochondrion
D	0005741	cellular_component	mitochondrial outer membrane
D	0005742	cellular_component	mitochondrial outer membrane translocase complex
D	0008320	molecular_function	protein transmembrane transporter activity
D	0015031	biological_process	protein transport
D	0030150	biological_process	protein import into mitochondrial matrix
D	0045040	biological_process	protein insertion into mitochondrial outer membrane
D	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
e	0005739	cellular_component	mitochondrion
e	0005741	cellular_component	mitochondrial outer membrane
e	0005742	cellular_component	mitochondrial outer membrane translocase complex
e	0008320	molecular_function	protein transmembrane transporter activity
e	0015031	biological_process	protein transport
e	0030150	biological_process	protein import into mitochondrial matrix
e	0045040	biological_process	protein insertion into mitochondrial outer membrane
E	0005739	cellular_component	mitochondrion
E	0005741	cellular_component	mitochondrial outer membrane
E	0005742	cellular_component	mitochondrial outer membrane translocase complex
E	0008320	molecular_function	protein transmembrane transporter activity
E	0015031	biological_process	protein transport
E	0030150	biological_process	protein import into mitochondrial matrix
E	0045040	biological_process	protein insertion into mitochondrial outer membrane
i	0005515	molecular_function	protein binding
i	0005739	cellular_component	mitochondrion
i	0005741	cellular_component	mitochondrial outer membrane
i	0005742	cellular_component	mitochondrial outer membrane translocase complex
i	0005758	cellular_component	mitochondrial intermembrane space
i	0005829	cellular_component	cytosol
i	0006811	biological_process	monoatomic ion transport
i	0008320	molecular_function	protein transmembrane transporter activity
i	0015031	biological_process	protein transport
i	0015288	molecular_function	porin activity
i	0030150	biological_process	protein import into mitochondrial matrix
i	0045040	biological_process	protein insertion into mitochondrial outer membrane
i	0046930	cellular_component	pore complex
i	0055085	biological_process	transmembrane transport
I	0005515	molecular_function	protein binding
I	0005739	cellular_component	mitochondrion
I	0005741	cellular_component	mitochondrial outer membrane
I	0005742	cellular_component	mitochondrial outer membrane translocase complex
I	0005758	cellular_component	mitochondrial intermembrane space
I	0005829	cellular_component	cytosol
I	0006811	biological_process	monoatomic ion transport
I	0008320	molecular_function	protein transmembrane transporter activity
I	0015031	biological_process	protein transport
I	0015288	molecular_function	porin activity
I	0030150	biological_process	protein import into mitochondrial matrix
I	0045040	biological_process	protein insertion into mitochondrial outer membrane
I	0046930	cellular_component	pore complex
I	0055085	biological_process	transmembrane transport
j	0005515	molecular_function	protein binding
j	0005739	cellular_component	mitochondrion
j	0005741	cellular_component	mitochondrial outer membrane
j	0005742	cellular_component	mitochondrial outer membrane translocase complex
j	0006886	biological_process	intracellular protein transport
j	0008320	molecular_function	protein transmembrane transporter activity
j	0015031	biological_process	protein transport
j	0030150	biological_process	protein import into mitochondrial matrix
j	0045040	biological_process	protein insertion into mitochondrial outer membrane
J	0005515	molecular_function	protein binding
J	0005739	cellular_component	mitochondrion
J	0005741	cellular_component	mitochondrial outer membrane
J	0005742	cellular_component	mitochondrial outer membrane translocase complex
J	0006886	biological_process	intracellular protein transport
J	0008320	molecular_function	protein transmembrane transporter activity
J	0015031	biological_process	protein transport
J	0030150	biological_process	protein import into mitochondrial matrix
J	0045040	biological_process	protein insertion into mitochondrial outer membrane
k	0005515	molecular_function	protein binding
k	0005739	cellular_component	mitochondrion
k	0005741	cellular_component	mitochondrial outer membrane
k	0005742	cellular_component	mitochondrial outer membrane translocase complex
k	0006626	biological_process	protein targeting to mitochondrion
k	0008320	molecular_function	protein transmembrane transporter activity
k	0015031	biological_process	protein transport
k	0045040	biological_process	protein insertion into mitochondrial outer membrane
k	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
k	0071806	biological_process	protein transmembrane transport
K	0005515	molecular_function	protein binding
K	0005739	cellular_component	mitochondrion
K	0005741	cellular_component	mitochondrial outer membrane
K	0005742	cellular_component	mitochondrial outer membrane translocase complex
K	0006626	biological_process	protein targeting to mitochondrion
K	0008320	molecular_function	protein transmembrane transporter activity
K	0015031	biological_process	protein transport
K	0045040	biological_process	protein insertion into mitochondrial outer membrane
K	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
K	0071806	biological_process	protein transmembrane transport
l	0005739	cellular_component	mitochondrion
l	0005741	cellular_component	mitochondrial outer membrane
l	0005742	cellular_component	mitochondrial outer membrane translocase complex
l	0008320	molecular_function	protein transmembrane transporter activity
l	0015031	biological_process	protein transport
l	0030150	biological_process	protein import into mitochondrial matrix
l	0045040	biological_process	protein insertion into mitochondrial outer membrane
l	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
L	0005739	cellular_component	mitochondrion
L	0005741	cellular_component	mitochondrial outer membrane
L	0005742	cellular_component	mitochondrial outer membrane translocase complex
L	0008320	molecular_function	protein transmembrane transporter activity
L	0015031	biological_process	protein transport
L	0030150	biological_process	protein import into mitochondrial matrix
L	0045040	biological_process	protein insertion into mitochondrial outer membrane
L	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
m	0005739	cellular_component	mitochondrion
m	0005741	cellular_component	mitochondrial outer membrane
m	0005742	cellular_component	mitochondrial outer membrane translocase complex
m	0008320	molecular_function	protein transmembrane transporter activity
m	0015031	biological_process	protein transport
m	0030150	biological_process	protein import into mitochondrial matrix
m	0045040	biological_process	protein insertion into mitochondrial outer membrane
M	0005739	cellular_component	mitochondrion
M	0005741	cellular_component	mitochondrial outer membrane
M	0005742	cellular_component	mitochondrial outer membrane translocase complex
M	0008320	molecular_function	protein transmembrane transporter activity
M	0015031	biological_process	protein transport
M	0030150	biological_process	protein import into mitochondrial matrix
M	0045040	biological_process	protein insertion into mitochondrial outer membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue MC3 I 401

Chain	Residue
A	ARG330
B	THR104
B	GLN122
I	ARG85
I	ARG330
I	VAL332
J	THR104

site_id	AC2
Number of Residues	7
Details	binding site for residue MC3 i 401

Chain	Residue
i	GLN311
i	LEU328
i	ARG330
i	VAL332
j	THR104
a	ARG330
a	PHE340

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	68
Details	TOPO_DOM: Cytoplasmic => ECO:0000250

Chain	Residue	Details
E	SER2-LYS19
M	SER2-LYS19
e	SER2-LYS19
m	SER2-LYS19

site_id	SWS_FT_FI2
Number of Residues	84
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
E	ILE20-TRP41
M	ILE20-TRP41
e	ILE20-TRP41
m	ILE20-TRP41

site_id	SWS_FT_FI3
Number of Residues	72
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000250

Chain	Residue	Details
E	ALA42-VAL60
M	ALA42-VAL60
e	ALA42-VAL60
m	ALA42-VAL60

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: N-acetylmethionine => ECO:0007744\|PubMed:22814378

Chain	Residue	Details
D	MET1
L	MET1
d	MET1
l	MET1
b	SER44
b	SER46
j	SER44
j	SER46

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)