6UC2
Human IMPDH2 treated with ATP and 2 mM GTP. Free canonical octamer reconstruction.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Inosine-5'-monophosphate dehydrogenase 2 | polymer | 519 | 56480.5 | 8 | UniProt (P12268) Pfam (PF00478) Pfam (PF00571) | Homo sapiens (Human) | IMPDH 2,IMPDH-II |
| 2 | AA, BA, DA, EA, I... (G, H, A, B, C...) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 16 | Chemie (GTP) | |||
| 3 | CA, FA, K, N, Q... (G, H, A, B, C...) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 8 | Chemie (ATP) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 514 (UniProt: P12268)
| PDB | External Database | Details |
|---|---|---|
| Ser -4 | - | expression tag |
| Glu -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 451844.0 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 12428.3 | |
| All* | Total formula weight | 464272.3 |
