6U9W
Cryo electron microscopy structure of the ATP-gated rat P2X7 ion channel in the ATP-bound, open state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | P2X purinoceptor 7 | polymer | 609 | 69904.0 | 3 | UniProt (Q64663) Pfam (PF00864) Pfam (PF20478) | Rattus norvegicus (Rat) | P2X7,ATP receptor,P2Z receptor,Purinergic receptor |
| 2 | D, E, F, G, H... (D, E, F, G, H...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 3 | GA, HA, J, K, U... (C, A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | IA, L, W (C, A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 5 | JA, KA, M, N, X... (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 6 | LA, O, Z (C, A, B) | O-[(R)-[(2S)-2-(hexadecanoyloxy)-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl]-D-serine | non-polymer | 764.0 | 3 | Chemie (Q3G) PubChem (52925997) PubChem (145946117) PubChem (75958913) | |||
| 7 | AA, BA, CA, DA, MA... (B, C, A) | PALMITIC ACID | non-polymer | 256.4 | 12 | Chemie (PLM) | |||
| 8 | EA, FA, T (B, C, A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) |
Sequence modifications
A, B, C: 1 - 595 (UniProt: Q64663)
| PDB | External Database | Details |
|---|---|---|
| Ser 596 | - | expression tag |
| Asn 597 | - | expression tag |
| Ser 598 | - | expression tag |
| Ala 599 | - | expression tag |
| Val 600 | - | expression tag |
| Asp 601 | - | expression tag |
| Ala 602 | - | expression tag |
| Gly 603 | - | expression tag |
| Leu 604 | - | expression tag |
| Glu 605 | - | expression tag |
| Val 606 | - | expression tag |
| Leu 607 | - | expression tag |
| Phe 608 | - | expression tag |
| Gln 609 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 209712.0 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 2546.4 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 9940.0 | |
| All* | Total formula weight | 222198.5 |
