6U9W
Cryo electron microscopy structure of the ATP-gated rat P2X7 ion channel in the ATP-bound, open state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | P2X purinoceptor 7 | polymer | 609 | 69904.0 | 3 | UniProt (Q64663) Pfam (PF00864) Pfam (PF20478) In PDB | Rattus norvegicus (Rat) | P2X7,ATP receptor,P2Z receptor,Purinergic receptor |
2 | D, E, F, G, H... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
3 | C, A, B | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
4 | C, A, B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
5 | C, A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
6 | C, A, B | O-[(R)-[(2S)-2-(hexadecanoyloxy)-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl]-D-serine | non-polymer | 764.0 | 3 | Chemie (Q3G) | |||
7 | B, C, A | PALMITIC ACID | non-polymer | 256.4 | 12 | Chemie (PLM) | |||
8 | B, C, A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) |
Sequence modifications
A, B, C: 1 - 595 (UniProt: Q64663)
PDB | External Database | Details |
---|---|---|
Ser 596 | - | expression tag |
Asn 597 | - | expression tag |
Ser 598 | - | expression tag |
Ala 599 | - | expression tag |
Val 600 | - | expression tag |
Asp 601 | - | expression tag |
Ala 602 | - | expression tag |
Gly 603 | - | expression tag |
Leu 604 | - | expression tag |
Glu 605 | - | expression tag |
Val 606 | - | expression tag |
Leu 607 | - | expression tag |
Phe 608 | - | expression tag |
Gln 609 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 209712.0 | |
Branched | Number of molecules | 6 |
Total formula weight | 2546.4 | |
Non-Polymers* | Number of molecules | 33 |
Total formula weight | 9940.0 | |
All* | Total formula weight | 222198.5 |