6U9V
Cryo electron microscopy structure of the ATP-gated rat P2X7 ion channel in the apo, closed state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | P2X purinoceptor 7 | polymer | 609 | 69904.0 | 3 | UniProt (Q64663) Pfam (PF00864) Pfam (PF20478) | Rattus norvegicus (Rat) | |
| 2 | D, E, F, G, H... (D, E, F, G, H...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 3 | J, K, L (J, K, L) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 3 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | alpha-maltose | ||
| 4 | M, MA, Z (A, C, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
| 5 | AA, BA, N, NA, O... (B, A, C) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 6 | CA, DA, EA, P, PA... (B, A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 7 | FA, S, SA (B, A, C) | O-[(R)-[(2S)-2-(hexadecanoyloxy)-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl]-D-serine | non-polymer | 764.0 | 3 | Chemie (Q3G) | |||
| 8 | GA, HA, IA, JA, KA... (B, A, C) | PALMITIC ACID | non-polymer | 256.4 | 18 | Chemie (PLM) |
Sequence modifications
A, B, C: 1 - 595 (UniProt: Q64663)
| PDB | External Database | Details |
|---|---|---|
| Ser 596 | - | expression tag |
| Asn 597 | - | expression tag |
| Ser 598 | - | expression tag |
| Ala 599 | - | expression tag |
| Val 600 | - | expression tag |
| Asp 601 | - | expression tag |
| Ala 602 | - | expression tag |
| Gly 603 | - | expression tag |
| Leu 604 | - | expression tag |
| Glu 605 | - | expression tag |
| Val 606 | - | expression tag |
| Leu 607 | - | expression tag |
| Phe 608 | - | expression tag |
| Gln 609 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 209712.0 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 3573.3 | |
| Non-Polymers* | Number of molecules | 39 |
| Total formula weight | 10620.6 | |
| All* | Total formula weight | 223906.0 |
