6U9S
Crystal structure of human CD81 large extracellular loop in complex with 5A6 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | 5A6 FAB Heavy Chain | polymer | 232 | 24620.7 | 2 | Mus musculus (Mouse) | ||
| 2 | B, E (B, E) | 5A6 FAB Light Chain | polymer | 219 | 24186.0 | 2 | Mus musculus (Mouse) | ||
| 3 | C, F (C, F) | CD81 antigen | polymer | 98 | 10853.0 | 2 | UniProt (P60033) Pfam (PF00335) | Homo sapiens (Human) | 26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1,Tetraspanin-28,Tspan-28 |
| 4 | G, H, I (A, B, E) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | J, K, L, M, N... (A, B, C, D, E...) | water | water | 18.0 | 358 | Chemie (HOH) |
Sequence modifications
C, F: 112 - 200 (UniProt: P60033)
| PDB | External Database | Details |
|---|---|---|
| Glu 110 | - | expression tag |
| Thr 111 | - | expression tag |
| Ser 201 | - | expression tag |
| His 202 | - | expression tag |
| His 203 | - | expression tag |
| His 204 | - | expression tag |
| His 205 | - | expression tag |
| His 206 | - | expression tag |
| His 207 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 119319.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 119595.6 |
