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6U9S

Crystal structure of human CD81 large extracellular loop in complex with 5A6 Fab

Functional Information from GO Data
ChainGOidnamespacecontents
C0016020cellular_componentmembrane
F0016020cellular_componentmembrane
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue GOL A 401
ChainResidue
AILE107
ATYR108
AHOH514
AHOH544
BGLU61
CLYS171

site_idAC2
Number of Residues4
Detailsbinding site for residue GOL B 301
ChainResidue
BASP88
BLYS45
BARG67
BGLU87

site_idAC3
Number of Residues5
Detailsbinding site for residue GOL E 301
ChainResidue
ELYS45
EGLN51
EPRO65
EGLU87
EASP88

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
ChainResidueDetails
BTYR197-HIS203
ATYR200-HIS206

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsSITE: Important for interaction with integrin => ECO:0000269|PubMed:27993971
ChainResidueDetails
CLYS116
CLYS144
CLYS148
FLYS116
FLYS144
FLYS148

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PDB entries from 2024-10-30

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