6U8N

Human IMPDH2 treated with ATP, IMP, and NAD+. Fully extended filament segment reconstruction.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (I, A, J, B, K...)	Inosine-5'-monophosphate dehydrogenase 2	polymer	519	56480.5	16	UniProt (P12268) Pfam (PF00478) Pfam (PF00571)	Homo sapiens (Human)	IMPDH 2,IMPDH-II
2	CA, DA, GA, HA, KA... (D, E, F, G, A...)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	16	Chemie (ATP)
3	AA, EA, IA, MA, QA... (C, D, E, F, G...)	INOSINIC ACID	non-polymer		348.2	8	Chemie (IMP)
4	BA, FA, JA, NA, RA... (C, D, E, F, G...)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	8	Chemie (NAD)

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	903688.0
Non-Polymers*	Number of molecules	32
	Total formula weight	16207.9
All*	Total formula weight	919895.9

*Water molecules are not included.