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6U8N

Human IMPDH2 treated with ATP, IMP, and NAD+. Fully extended filament segment reconstruction.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1I, A, J, B, K...Inosine-5'-monophosphate dehydrogenase 2polymer51956480.516UniProt (P12268)
Pfam (PF00478)
Pfam (PF00571)
In PDB
Homo sapiens (Human)IMPDH 2,IMPDH-II
2D, E, F, G, A...ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.216Chemie (ATP)
3C, D, E, F, G...INOSINIC ACIDnon-polymer348.28Chemie (IMP)
4C, D, E, F, G...NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.48Chemie (NAD)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains16
Total formula weight903688.0
Non-Polymers*Number of molecules32
Total formula weight16207.9
All*Total formula weight919895.9
*Water molecules are not included.

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PDB entries from 2024-04-24

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