6U80

Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	WD repeat-containing protein 5	polymer	311	34232.8	2	UniProt (P61964) Pfam (PF00400) In PDB	Homo sapiens (Human)	BMP2-induced 3-kb gene protein
2	A, B	5-bromo-N-(4-hydroxy[1,1'-biphenyl]-3-yl)-2-methoxybenzene-1-sulfonamide	non-polymer		434.3	2	Chemie (Q1J)
3		water	water		18.0	752	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68465.7
Non-Polymers*	Number of molecules	2
	Total formula weight	868.6
All*	Total formula weight	69334.3

*Water molecules are not included.